Lyrica pregabalin 300mg

Lyrica Pregabalin 300mg capsules contain the active ingredient pregabalin, manufactured by Pfizer. It is a gamma-aminobutyric acid (GABA) analogue used to treat several neurological and pain conditions by modulating calcium channels and reducing the release of excitatory neurotransmitters.

How Lyrica Pregabalin 300mg Works: Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system. This reduces calcium influx and decreases the release of excitatory neurotransmitters such as glutamate, substance P, and noradrenaline, resulting in analgesic, anticonvulsant, and anxiolytic effects.

Main Uses:

• Neuropathic pain (diabetic peripheral neuropathy, postherpetic neuralgia)
• Fibromyalgia
• Adjunctive therapy for partial-onset seizures in epilepsy
• Generalized anxiety disorder (GAD) in approved regions

Dosage and Administration The 300mg strength is typically used after titration from lower doses. Usual daily dose ranges from 150mg to 600mg, divided into 2 or 3 doses. Capsules should be swallowed whole with water and can be taken with or without food. Dose must be adjusted in patients with kidney impairment. Never stop suddenly — taper under medical supervision.

Quality and Formulation Lyrica 300mg capsules are orange/white hard gelatin capsules imprinted with “Pfizer” and “PGN 300”. Produced under strict GMP standards by Pfizer (original brand) with generics also available.

Warnings and Precautions Pregabalin is a controlled substance in many countries due to potential for misuse, dependence, and abuse. Common side effects include dizziness, drowsiness, weight gain, peripheral edema, blurred vision, and dry mouth. It can cause respiratory depression when combined with opioids, benzodiazepines, or alcohol.

Risk of suicidal thoughts, severe allergic reactions, and angioedema exists. Not recommended during pregnancy unless clearly necessary. May impair driving and operating machinery.

Lyrica Pregabalin 300mg should only be used under medical supervision with regular follow-up.